Figure 4.

(A) Average time constants at −60 mV show little difference among roving patch locations for the perforated patch condition, but significant differences following whole-cell recording. (B) Similarly, times to peak (Tpk) current increase at apical and middle positions following patch rupture. (C) For salicylate-treated cells, time constants show no significant differences between perforated patch and whole-cell conditions. (D) Tpk shows no significant differences at basal and middle positions; however, a difference was observed at the apical position where Tpk was now shorter following patch rupture. Number of cells is noted. Statistical significance (p <; t-test), where present, between pre- and postpatch rupture is shown for each location. To see this figure in color, go online.