Cable model time constants (τ) of perforated (A) and whole-cell (B) patch responses induced by step voltages of the roving loose patch electrode. Note increase in time constants (τ) after change from perforated patch parameters to whole-cell parameters (see Model Results), and an apparent rise in voltage dependency similar to what is seen with the biophysical data. (C) and (D) show corresponding measures of whole-cell NLC measured with recording whole-cell electrode (Qmax, Vh, z: 2.78/2.94 pC, −40.7/−56.3 mV, 0.60/0.60). Compare to Fig. 2. To see this figure in color, go online.