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. Author manuscript; available in PMC: 2016 Feb 3.
Published in final edited form as: Structure. 2015 Feb 3;23(2):257–269. doi: 10.1016/j.str.2014.11.021

Figure 7. AFM images reveal variable distances between the catalytic and HPX domains of MT1-MMP, suggesting flexible tethering and diffusion of the domains.

Figure 7

(A–C) Features with distances between high points of the domains of 4.2 nm (A), 6.1 nm.(B), and 8 nm (C). The vertical scale rises to 4 nm and the lateral scale bar represents 5 nm.

(D) The histogram shows the distribution of peak-to-peak distances (N = 134 features) between high points of adjoining domains in 150 mM NaCl, 10 mM CaCl2, at pH 7.5. The bin size is 0.45 nm.