Table 1.
Natural history of asymptomatic kidney stones
| Ref. | Study type | No. of patients | Follow-up | Disease progression (stone growth) | Symptomatic episode | Need for intervention |
| Glowacki et al[1] | Retrospective | 107 | 31.6 mo | NA | 31.8% | 16.8% |
| Hübner et al[3] | Retrospective | 80 | 7.4 yr | 45% | 68% | 83% |
| Keeley et al[5] | Randomized prospective | 200 | 2.2 yr | NA | 21% | 10% |
| Burgher et al[2] | Retrospective | 300 | 3.26 yr | 77% | NA | 26% |
| Inci et al[4] | Retrospective | 24 | 52.3 mo | 33.3% | 41.7% | 11% |
NA: Not available.