Table 2.
Characteristic of study population and differences between hemodialysis patients and no-hemodialysis n (%)
| Total | Dialysis patients | Patients with maintained | P | |
| (n = 630) | (n = 160) | Renal function | ||
| (n = 470) | ||||
| Women | 336 (53.3) | 72 | 264 | 0.0141 |
| Obese patients | 196 (31.1) | 24 | 172 | < 0.0001 |
| Patients with GFR < 90 | 514 (81.6) | 160 | 354 | < 0.0001 |
| NAFLD patients | 256 (40.6) | 28 | 228 | < 0.0001 |
| MTHFR group | ||||
| Wild genotype | 94 (14.9) | 36 | 58 | 0.0161 |
| MTHFR C677T | 118 (18.7) | 28 | 90 | |
| MTHFR 1298 AC | 76 (12.1) | 20 | 56 | |
| Compound heterozygous C677T and A1298C | 158 (25.1) | 40 | 118 | |
| MTHFR 1298 CC | 80 (12.7) | 20 | 60 | |
| MTHFR 677TT | 104 (16.5) | 16 | 88 | |
| Age, yr | 54.60 ± 16.35 | 67.48 ± 14.57 | 50.22 ± 14.51 | < 0.0001 |
| BMI, kg/m2 | 27.70 ± 5.76 | 25.29 ± 3.97 | 28.52 ± 6.04 | < 0.0001 |
| Blood glucose, mg/dL | 96.42 ± 26.42 | 95.33 ± 34.80 | 96.79 ± 22.91 | 0.545 |
| Blood urea, mg/dL | 52.47 ± 35.74 | 100.45 ± 41.07 | 36.13 ± 9.40 | < 0.0001 |
| Creatinin, mg/dL | 2.36 ± 2.98 | 6.75 ± 2.99 | 0.86 ± 0.21 | < 0.0001 |
| GFR | 62.46 ± 35.32 | 9.28 ± 3.60 | 80.56 ± 19.38 | < 0.0001 |
| Triglycerides, mg/dL | 112.16 ± 64.71 | 131.90 ± 87.21 | 105.44 ± 53.48 | < 0.0001 |
| Total cholesterol, mg/dL | 199.72 ± 44.43 | 175.80 ± 42.67 | 207.86 ± 42.05 | < 0.0001 |
| HDL cholesterol, mg/dL | 54.81 ± 18.10 | 48.20 ± 15.63 | 57.07 ± 18.34 | < 0.0001 |
| LDL cholesterol, mg/dL | 122.75 ± 39.63 | 101.22 ± 33.04 | 130.09 ± 39.05 | < 0.0001 |
| AST, U/L | 21.81 ± 11.16 | 14.38 ± 4.07 | 24.34 ± 11.66 | < 0.0001 |
| ALT, U/L | 16.54 ± 5.63 | 12.75 ± 4.15 | 17.83 ± 5.49 | < 0.0001 |
| γGT, U/L | 33.10 ± 32.11 | 31.78 ± 19.18 | 33.55 ± 35.46 | 0.546 |
| Insulin | 11.84 ± 9.73 | 11.44 ± 10.77 | 11.98 ± 9.36 | 0.547 |
| HOMA | 3.02 ± 3.30 | 3.08 ± 3.94 | 3.00 ± 3.05 | 0.797 |
| PTH, pg/mL | 84.58 ± 105.79 | 162.38 ± 178.81 | 57.99 ± 36.85 | < 0.0001 |
| hsCRP, mg/dL | 3.52 ± 7.01 | 2.62 ± 2.45 | 3.82 ± 7.98 | 0.107 |
| Albumin, g/dL | 4.60 ± 0.37 | 4.64 ± 0.35 | 4.58 ± 0.37 | 0.119 |
| Albumin, % | 62.39 ± 3.60 | 62.60 ± 3.03 | 62.31 ± 3.77 | 0.388 |
| RRI | 0.62 ± 0.06 | 0.68 ± 0.03 | 0.60 ± 0.06 | < 0.0001 |
| EF,% | 65.93 ± 9.99 | 61.03 ± 12.62 | 67.87 ± 7.95 | < 0.0001 |
| E/A | 1.14 ± 0.33 | 1.03 ± 0.39 | 1.18 ± 0.30 | < 0.0001 |
| LVMM/m2 | 104.95 ± 42.10 | 135.37 ± 55.56 | 93.84 ± 28.91 | < 0.0001 |
| AMDS | 34.51 ± 3.09 | 35.93 ± 1.69 | 34.02 ± 3.31 | < 0.0001 |
| Homocysteine, μmol/L | 2.1 ± 5.4 | 36.8 ± 8.5 | 21.2 ± 7.7 | < 0.0001 |
1
Pearson χ2. GFR: Glomerular filtration rate; BMI: Body mass index; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; γGT: γ-Glutamyl transpeptidase; hsCRP: High-sensitivity C-reactive protein; RRI: Renal resistive index; EF: Ejection fraction; LVMM: Left ventricular mass myocardial; AMDS: Adherence mediterranean diet score; MTHFR: Methylenetetrahydrofolate reductase; PTH: Parathyroid hormone; HOMA: Homoeostasis model-insulin resistance index; NAFLD: Non-alcoholic fatty liver disease.