Figure 4.

Rescue of the sax-7gtl-2 Ric phenotype with tissue-specific sax-7 expression reveals a requirement for sax-7 in neurons. Neuronal expression of sax-7 by the unc-119 promoter suppresses sax-7gtl-2 resistance to Aldicarb to the same level as that of the full-length sax-7 gene, unlike sax-7 expression in body-wall muscle or hyp7. Three independent transgenic lines were analyzed for each construct assessed. The rescue abilities of these constructs are similar in all sax-7gtl-2 strains. For simplicity, only data for the sax-7(eq1) gtl-2(tm1463) background are shown. Error bars show the standard error of the mean of at least 12 sample sets, where n = 25 for each set.