Table 1. Predicted genes found in fine mapped regions of hms1 and hms2.
Locus | Gene namea | Gene annotationa | Predicted functional roleb | Sterility phenotype in Arabidopsis? |
---|---|---|---|---|
hms1 | Migut.F01605 and Migut.F01606 | Skp1 family | Cell cycle regulation, component of SCF ubiquitin–ligase complexc | Arabidopsis Skp1 homolog (ASK1) mutant causes male sterility via defects in male meiosisd |
Migut.F01607 | Iron–sulfur cluster biosynthesis | Iron–sulfur cluster binding, structural molecule activity | ||
Migut.F01608 | 4′-phosphopantetheinyl transferase superfamily | Involved in metabolic processes, macromolecule biosynthesis | ||
Migut.F01609 | None | |||
Migut.F01610 | Leucine rich repeat (LRR) | Kinase activity, signal transduction; diverse roles in plant development and disease resistancee | Mutations in EMS1/EXS (1 of >200 LRR genes in Arabidopsis) causes male sterility when microsporocytes do not undergo proper cytokinesisf | |
Migut.F01611 | PPR repeat | Organellar RNA processing, embryonic developmentg | Some members of this large gene family (450 in Arabidopsis) are involved in fertility restoration of CMS plantsh | |
Migut.F01612 | F-box | Component of SCF ubiquitin–ligase complex, targets specific proteins for degradation | Among this large gene family (>600 in Arabidopsis), COI1 mutants are male sterilei, FBL17 mutants inhibit male germline proliferationj, the rice hybrid sterility gene SaF encodes an F-box proteink | |
Migut.F01613 | None | |||
Migut.F01614 | Yip1 domain; Golgi membrane protein | Involved in the trans-Golgi networkl | ||
Migut.F01615 | Amino acid kinase family; gamma-glutamyl kinase | Amino acid biosynthesis | ||
hms2 | Migut.M00294 | Protein kinase domain; cdc2-related protein kinase | Cyclin-dependent kinase (CDK)-like proteinm, cell cycle regulation | Arabidopsis cdc2 mutant (CDKA;1) is male sterile because it fails to progress through the second mitosis in male gametogenesisn |
Migut.M00295 | Cellulase (glycosyl hydrolase family 5) | Involved in carbohydrate metabolism, hydrolase activity | ||
Migut.M00296 | None | |||
Migut.M00297 | RNA polymerase Rpb2 | Encodes a subunit of DNA-dependent RNA polymerase II | ||
Migut.M00298 | GH3 auxin-responsive promoter | Involved in red light-specific hypocotyl elongation |
Unless a citation is provided, functional descriptions are taken from TAIR (arabidopsis.org) for the gene’s closest Arabidopsis thaliana BLAST hit.
Xie et al. 1999.