Table 1. Characteristics of and relationships between individuals affected by histologically-confirmed glioma in each family.
| Relationship | Histology | Age Dx | Sex | Sequenced |
|---|---|---|---|---|
| Family A | ||||
| Proband | Oliogdendroglioma | 48 | Female | Yes |
| Sibling | Astrocytoma | 33 | Male | Yes |
| P 2nd Cousin | Ependymoma | 20 | Female | No |
| Family B | ||||
| Proband | Astrocytoma | 40 | Female | Yes |
| P 1st Cousin | Oliogendrglioma | 30 | Female | Yes |
| Family C | ||||
| Proband | Anaplastic Astro | 40 | Male | Yes |
| Sibling | GBM | 46 | Male | Yes |
| Sibling | Astrocytoma | 16 | Female | No |
| Family D | ||||
| Proband | GBM | 54 | Female | Yes |
| Father | UNK Glioma | 31 | Male | No |
| P Aunt | GBM | 55 | Female | No |
| Family E | ||||
| Proband | Anaplastic Astro | 39 | Male | Yes |
| Sibling | Oligodendroglioma | 27 | Female | Yes |
| Family F | ||||
| Proband | GBM | 61 | Male | Yes |
| Sibling | GBM | 52 | Female | Yes |
| Family G | ||||
| Proband | Anaplastic Oligo | 28 | Male | Yes |
| Father | Anaplastic Astro | 29 | Male | Yes |
| P Grandfather | UNK Glioma | 50 | Male | No |
| Family H | ||||
| Proband | GBM | 59 | Male | Yes |
| Sibling | UNK Glioma | 42 | Male | No |
| Family I | ||||
| Proband | Anaplastic Oligo | 58 | Female | Yes |
| Nephew | Oligodendroglioma | 32 | Male | Yes |
| Family J | ||||
| Proband | Anaplastic Astro | 27 | Female | Yes |
| Sibling | Oligoastrocytoma | 38 | Male | Yes |
| Family K | ||||
| Proband | Anaplastic Oligo | 65 | Male | No |
| M Aunt | GBM | 82 | Female | Yes |
| M Great Aunt | GBM | 79 | Female | No |
| M Great Aunt | Anaplastic Astro | 81 | Female | No |
| M 1st Cousin Once Removed | UNK Glioma | 63 | Female | No |
| M 1st Cousin Once Removed | GBM | 61 | Male | No |
| Family L | ||||
| Proband | Astrocytoma | 39 | Female | Yes |
| M Aunt | GBM | 66 | Female | Yes |
| Family M | ||||
| Proband | GBM | 66 | Female | Yes |
| M Aunt | GBM | 59 | Female | No |
| Family N | ||||
| Proband | GBM | 66 | Male | Yes |
| Sibling | GBM | 53 | Male | No |
| Family O | ||||
| Proband | Astrocytoma | 43 | Female | Yes |
| Mother | UNK Glioma | 27 | Female | No |
| Sibling | GBM | 45 | Male | No |
| Family P | ||||
| Proband | Anaplastic Astro | 28 | Male | Yes |
| Identical Twin | Oligoastrocytoma | 18 | Male | Yes |
| Family Q | ||||
| Proband | GBM | 10 | Female | Yes |
| M Grandmother | GBM | 65 | Female | No |
| Family R | ||||
| Proband | GBM | 44 | Female | Yes |
| Sibling | GBM | 22 | Male | No |
| Niece | Astrocytoma | 24 | Female | Yes |
| Niece | Astrocytoma | 4 | Female | No |
| M Aunt | UNK Glioma | 11 | Female | No |
| M 1st Cousin | Astrocytoma | 38 | Female | Yes |
| M 2nd Cousin Once Removed | UNK Glioma | 49 | Female | No |
| M 2nd Cousin Once Removed | UNK Glioma | 46 | Female | No |
| P 1st Cousin Twice Removed | UNK Glioma | 78 | Male | No |
| P 2nd Cousin Once Removed | UNK Glioma | 4 | Male | No |
| Family S | ||||
| Proband | Oligodendroglioma | 37 | Female | Yes |
| Sibling | Ana Oligoastro | 41 | Male | Yes |
| Family T | ||||
| Proband | GBM | 68 | Female | Yes |
| Mother | GBM | 78 | Female | No |
| M Uncle | UNK Glioma | 49 | Male | No |
P, Paternal; M, Maternal; Dx, Diagnosis; UNK, unknown; Ana, anaplastic; GBM, glioblastoma multiforme; Astro, astrocytoma.