Table 2.
CNV analysis of the 22 genes in NSCLC tumor tissue.
| Genes | No change | Duplication | Triplication | # of amplified samples | Heterozygote Deletion | Homozygote Deletion | Amplification % |
|---|---|---|---|---|---|---|---|
| ESR1 | 77 | 4 | 0 | 4 | 1 | 0 | 4.9 |
| EGFR | 67 | 7 | 8 | 15 | 0 | 0 | 18.3 |
| ZNF703 | 43 | 28 | 10 | 38 | 1 | 0 | 46.3 |
| FGFR1 | 68 | 6 | 3 | 9 | 5 | 0 | 11.1 |
| ADAM9 | 69 | 3 | 4 | 7 | 6 | 0 | 8.5 |
| IKBKB | 73 | 7 | 2 | 9 | 0 | 0 | 11.1 |
| PRDM14 | 58 | 24 | 10 | 34 | 0 | 0 | 41.5 |
| MTDH | 64 | 12 | 4 | 16 | 2 | 0 | 19.5 |
| MYC | 55 | 18 | 9 | 27 | 0 | 0 | 32.9 |
| CCND1 | 72 | 2 | 8 | 10 | 0 | 0 | 12.2 |
| C11ORF30 | 68 | 7 | 3 | 10 | 4 | 0 | 12.2 |
| CDH1 | 70 | 7 | 4 | 11 | 1 | 0 | 13.4 |
| CPD | 69 | 6 | 2 | 8 | 5 | 0 | 9.8 |
| MED1 | 62 | 9 | 5 | 14 | 4 | 2 | 17.1 |
| ERBB2 | 71 | 6 | 5 | 11 | 0 | 0 | 13.4 |
| CDC6 | 68 | 9 | 4 | 13 | 1 | 0 | 15.9 |
| TOP2A | 74 | 6 | 1 | 7 | 1 | 0 | 8.5 |
| MAPT | 75 | 3 | 2 | 5 | 2 | 0 | 6.1 |
| PPM1D | 62 | 12 | 4 | 16 | 4 | 0 | 19.5 |
| BIRC5 | 55 | 25 | 2 | 27 | 0 | 0 | 32.9 |
| CCNE1 | 64 | 13 | 5 | 18 | 0 | 0 | 22.1 |
| AURKA | 73 | 9 | 0 | 9 | 0 | 0 | 11.1 |