Table 3.
Multivariate analysis for overall survival
| Characteristics | Category | Hazard ratio† | 95% CI | P-value |
|---|---|---|---|---|
| ECOG | 0–1 | 1 | ||
| 2 | 9.526 | 2.587–20.493 | 0.003 | |
| Histology | Invasive ductal carcinoma | 1 | ||
| Others* | 3.547 | 1.205–10.444 | 0.022 | |
| Triple negative | Non-triple negative | 1 | ||
| Phenotype | Triple negative | 2.106 | 1.145–3.874 | 0.017 |
| Initial stage‡ | Stage I-IIIA | 1 | ||
| Stage IIIB-IIIC | 2.406 | 1.270–4.555 | 0.007 | |
| Pathologic | pCR | 1 | ||
| Response | Non-pCR | 8.204 | 1.810–19.112 | 0.047 |
| ABCB1 C3435T | CC + CT | 1 | ||
| TT | 0.245 | 0.059–1.026 | 0.054 |
Eastern Cooperative Oncology Group.
†
Hazard ratio was calculated by Cox's proportional hazard model. If the hazard ratio is >1, the hazard ratio can be thought of as the average increased risk of death compared with the reference group (upper line).
‡
According to the TNM classification of 2002 AJCC staging.
*
Among the 10 patients, 7 had invasive lobular carcinomas, 3 medullary carcinomas and 1 tubular carcinoma.