Skip to main content
. 2014 Dec 3;106(1):94–101. doi: 10.1111/cas.12562

Figure 5.

Figure 5

Phloroglucinol suppresses metastatic ability of breast cancer cells to lung. (a) Schematic experimental procedure for tail vein injection of cancer cells into athymic nude mice and treatment with vehicle or phloroglucinol. (b) Quantification of lung metastases foci generated by green fluorescent protein (GFP)-labeled metastatic MDA-MB231 cells after tail vein injection (n = 4). (c) H&E staining and GFP florescence of lung metastases foci after tail vein injection. (d, e) Immunohistochemistry for p-AKT (d) and p-ERK (e) in lung metastasized tumor tissues. (f) Kaplan–Meier survival curves of mice that were treated with phloroglucinol or vehicle after tail vein injection of cancer cells. Error bars represent mean ± SD. *P < 0.01 vs control.