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Comparison of gene usage and structural homologies of the variable heavy (VH) and variable light (VL) domains of recombinant Fab clones
| Fab | VH gene usage |
VL gene usage |
||||
|---|---|---|---|---|---|---|
| Nearest germline | Homology to germline % |
Nearest germline | Homology to germline % |
|||
| DNA | Protein | DNA | Protein | |||
| HBJ127 | VHQ52.a5.13 | 94.2 | 89.7 | IgVk8-30 | 96.7 | 93.1 |
| A18 | VHQ52.a5.13 | 92.8 | 88.7 | IgVk8-30 | 98.7 | 97.0 |
| B3 | VHQ52.a5.13 | 94.2 | 87.6 | IgVk8-30 | 99.7 | 99.0 |
| C17 | VHQ52.a5.13 | 93.2 | 88.7 | IgVk8-30 | 98.3 | 95.0 |
