Table 1.
Prevalence of human papillomavirus (HPV) in head and neck squamous cell carcinomas according to primary tumor site (n = 493)
| Primary site | Total no. | HPV-positive n (%) | Odds ratio† | 95% CI | P-value |
|---|---|---|---|---|---|
| Oropharynx | 163 | 56 (34.4) | Reference | ||
| Non-oropharynx (whole) | 330 | 12 (3.6) | 0.1 | 0.0400–0.1000 | <0.001 |
| Oral cavity | 57 | 0 (0.0) | 0.0 | 0.0008–0.2000 | <0.001 |
| Nasopharynx | 25 | 3 (12.0) | 0.3 | 0.0500–0.9000 | 0.035 |
| Hypopharynx | 171 | 6 (3.5) | 0.1 | 0.0200–0.2000 | <0.001 |
| Larynx | 77 | 3 (3.9) | 0.1 | 0.0200–0.3000 | <0.001 |
†
Univariate analysis was made by logistic regression model, except for oral cavity that was made by the Clopper–Pearson method. CI, confidence interval.