Fig. 1.

Decision tree for the immunostaining classification of diffuse large B-cell lymphoma (DLBCL). The germinal center B-cell-like (GCB) and non-GCB subtypes were classified according to the following standard: the cases were identified as GCB subtypes when the cases were CD10-positive. If they were both CD10-negative and BCL6-negative, then they belonged to the non-GCB subtype. If they were CD10-negative and BCL6-positive, the MUM1 immunostaining profile determined the subtype. The MUM1-positive cases were identified as non-GCB and MUM1-negative cases were identified as the GCB subtype.