Table 3.
Univariate analysis |
Multivariate analysis |
|||
---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Age, years | ||||
<60 | 1 (Ref.) | 0.4585 | ||
≥60 | 1.34 (0.63–3.01) | |||
Sex | ||||
Female | 1 (Ref.) | 0.4116 | ||
Male | 1.18 (0.78–1.72) | |||
Stage | ||||
I/II | 1 (Ref.) | <0.0001 | 1 (Ref.) | 0.0004 |
III/IV | 7.95 (2.78–33.47) | 6.20 (2.10–26.52) | ||
Histological type | ||||
Well differentiated | 1 (Ref.) | 0.9513 | ||
Poorly differentiated | 0.98 (0.46–2.11) | |||
Non-scirrhous | 1 (Ref.) | 0.1435 | ||
Scirrhous | 1.75 (0.82–3.70) | |||
Expression of miR-143 | ||||
Low | 1 (Ref.) | 0.0005 | 1 (Ref.) | 0.0141 |
High | 3.81 (1.80–8.29) | 2.62 (1.21–5.80) |
CI, confidence interval; HR, hazard ratio; miR-143, microRNA-143; Ref., reference.