Table 1.
Characteristics of subjects with esophageal squamous cell carcinoma (ESCC) and normal controls
| Variable | Serum samples (preoperative) |
P | Serum samples (postoperative) |
Serum samples (relapse) |
Paired tissue samples |
|
|---|---|---|---|---|---|---|
| Cases (n = 286) | Controls (n = 250) | Cases (n = 110) | Cases (n = 20) | Cases (n = 80) | ||
| Gender (n) | ||||||
| Male (%) | 184 (64.3) | 148 (59.2) | 0.222 | 77 (70.0) | 14 (70.0) | 54 (67.5) |
| Female (%) | 102 (35.7) | 102 (40.9) | 33 (30.0) | 6 (30.0) | 26 (32.5) | |
| Age (years) | ||||||
| ≤60 (%) | 149 (52.1) | 139 (55.6) | 0.417 | 50 (45.5) | 12 (60.0) | 29 (36.3) |
| >60 (%) | 137 (47.9) | 111 (44.4) | 60 (54.5) | 8 (40.0) | 51 (63.7) | |
| Stage (n) | ||||||
| I (%) | 48 (16.8) | 17 (15.5) | 2 (10.0) | 13 (16.3) | ||
| II (%) | 107 (37.4) | 50 (45.5) | 8 (40.0) | 29 (36.3) | ||
| III (%) | 94 (32.9) | 43 (39.1) | 10 (50.0) | 38 (47.5) | ||
| IV (%) | 37 (12.9) | |||||
P-values were determined using a two-sided χ2 test.