Figure 2.
Copy number (CN) change is summarized in each type of intraocular lymphoma (IOL). Frequency of CN gains (a) and losses (b), as well as CN neutral loss of heterozygosity (c) involving >3 Mb segments were calculated and plotted for each IOL type. *Copy number changes detected in >20% of diffuse large B-cell lymphomas; **CN changes detected in >20% of follicular lymphomas; ***CN changes detected in >20% of mucosa-associated lymphoid tissue lymphomas; ****CN changes detected in >20% of mantle cell lymphomas. Black arrows indicate common frequent (>50%) gain regions in primary IOL (PIOL), and in IOL with a central nervous system lesion at diagnosis (IOCNSL). SIOL, secondary IOL.