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. 2014 Apr 15;105(5):506–511. doi: 10.1111/cas.12398

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© 2014 The Authors. Cancer Science published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Xenografted tumor formations in nude mice. Nude mice were injected (s.c.) with (a) N-nitrosopyrrolidine (NPYR) transformed hId1-shRNA H8 cells, (b) NPYR transformed pGIPZ H8 cells (as control), (c) NPYR transformed pWPI-hId1 H8 cells, (d) NPYR transformed pWPI H8 cells (as control), and were photographed 8 weeks after injection. There were 10 mice in each group. Tumor size was presented as means ± SD. One representative mouse from each group is shown. Injection sites are indicated by arrowheads.