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Effect of doxycycline-induced HAI-1 expression on spontaneous metastasis after orthotopic transplantation of S2-CP8_HAI-1tet#1 cells
| Dox treatment | Infarction of liver† | Metastasis |
|||
|---|---|---|---|---|---|
| Positive | Liver and lungs | Liver only | Lungs only | ||
| No (n = 9) | 44% (4/9) | 56% (5/9) | 1/9 | 1/9 | 3/9 |
| Yes (n = 10) | 10% (1/10) | 0% (0/10) | |||
Infarction due to portal vein thrombosis. HAI-1, hepatocyte growth factor activator inhibitor type 1.
