Table 1.

Clinicopathological characteristics of extrahepatic cholangiocarcinoma patients according to stathmin expression

Factor	STMN1 low expression (n = 33)	STMN1 high expression (n = 47)	P-value
Age (years)
≤65	13	18	0.9211
>65	20	29
Sex
Male	23	35	0.6389
Female	10	12
Differentiation
Well	9	9	0.2563
Moderate	15	26
Poor	8	14
Tumor stage
T1–2	20	19	0.0745
T3–4	13	28
Lymph node metastasis
−	19	27	0.9908
+	14	20
Lymphatic invasion
−	7	4	0.1070
+	26	43
Venous invasion
−	12	4	0.002*
+	21	43
Distant metastasis
−	32	45	0.7740
+	1	2
Infiltration
α	0	2	0.1179
β	17	31
γ	15	14
TNM stage (UICC)
0, I	11	11	0.3297
II, III, IV	22	36
Nuclear p27
High expression	17	8	0.001
Low expression	16	39
Cytoplasmic p27
High expression	12	31	0.006
Low expression	21	15
Ki-67 labeling index (mean ± SD)	9.28 ± 13.5	62.1 ± 31.9	<0.0001

^*P < 0.05. STMN1, stathmin1; TNM, tumor–node–metastasis; UICC, Union for International Cancer Control.