Table 3.
Types of lymphoma | Clonal heterogeneity (−) | Clonal heterogeneity (+) | Detailed in | ||
---|---|---|---|---|---|
Gain | Loss | Gain | Loss | ||
MCL | — | — | 6q21, 8q13.3–q24.23† | 1p22.1–q12, 5q23.1,§ 7q36.3, 8p23.3–11.21, 9p24.3–q31.1,¶ 17p13.3–11.2†† | Figure S2 |
DLBCL | — | — | 19q13.12–.43 | 9p21.3,¶ 17p13. 2–11. 2†† | Figure2 |
FL | — | — | 2p16.1–14, 7p11.1, 7q31.1–.2, ‡ 8q22.1–24.23,† 9q12–34.3,‡ 10p15.3–13, 12p13.33–q21.1, 18p11.21–q23 | — | Figure S3 |
BL | 1q44, 12p13.33–q24.33, 15q22.32–15q25.1 | — | 1q25.2, 3q26.33–29, 13q31.3–32.3, 17q23.1–24.1 | 6p25.3–22.3, q13–21, 10q23.33–24.1, 11q23.3–25, 14q11.1–32.33,‡‡ 16q24.3, 17p13.3–q12†† | Figure S4 |
MALT | 1p36.33–.32, 2q14.3, 3p26.3–q29, 5q31.1, 10p12.31–.1, 18q11.2 -q23 | — | 13q34, 20p11.22–q12, 22q11.21 | 7q31.31–q34, 20p12.1 | Figure S5 |
PTCL-NOS | 5p15.1 | — | 7q21.11–q35,‡ 8q24.13–.21,† 9q33.3–34,‡ 16p13.3–11.1, 17q21.2–25.3 | 2p23.3, q21.3–37.3, 4p16.1–15.2, 5q14.3–34,§ 9p21.3–q31.1,¶ 10q11.1–q23.31, 12p13.1–.13, 13q21.31–34, 14q13.1–32.12,‡‡ 15q23, 17p13.3–11.2†† | Figure S6 |
All lymphomas | — | — | — | 9p21.3,¶ 17p13.3–11.2†† | Figure S7 |
Common aberrations more than two lymphomas are indicated in bold with underline.
Aberration is found in MCL, FL and PTCL-NOS;
aberration found in FL and PTCL-NOS;
aberration found in MCL and PTCL-NOS;
aberration found in MCL, DLBCL and PTCL-NOS;
aberration found in MCL, DLBCL, BL and PTCL-NOS;
aberration found in BL and PTCL-NOS. —, no region is identified; BL, Burkitt lymphoma; DLBCL, diffuse large B-cell lymphoma; FL, follicular lymphoma; MALT, mucosa-associated lymphoid tissue lymphoma; MCL, mantle cell lymphoma; PTCL-NOS, peripheral T-cell lymphoma, not otherwise specified.