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. 2014 Jun 27;105(7):862–869. doi: 10.1111/cas.12444

Table 2.

Olaratumab-related treatment-emergent adverse events across all cycles,

Number of patients, n (%)
Preferred term Cohort 1 (10 mg/kg) n = 3 Cohort 2 (20 mg/kg) n = 7 Cohort 3 (15 mg/kg) n = 6
Patients with any AE 1 (33.3) 6 (85.7) 1 (16.7)
Hematologic
 Anemia 0 1 (14.3) 0
 Leukopenia 0 1 (14.3) 0
Non-hematologic
 Aspartate aminotransferase increased 0 2 (28.6) 0
 Cough 1 (33.3) 0 0
 Dermatitis 0 0 1 (16.7)
 Diarrhea 0 1 (14.3) 0
 Fatigue 0 1 (14.3) 0
 Fibrin D-dimer increased 0 1 (14.3) 0
 Hyperglycemia 0 1 (14.3) 0
 Hypertension 0 1 (14.3) 0
 Proteinuria 0 3 (42.9) 1 (16.7)
 Rash 0 1 (14.3) 0
 Tumor hemorrhage 0 1 (14.3) 0

For each preferred term, each patient is counted only once per preferred term.

AEs with missing relationship to study drug were considered as related. AE, adverse event.