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. 2014 May 21;105(7):875–882. doi: 10.1111/cas.12426

Figure 2.

Figure 2

Glabridin (GLA) attenuates the invasive capacities of MDA-MB-231 and BT-549 cells. The migratory and invasive capacities of MDA-MB-231 and BT-549 cells were quantified by 24-well cell migration assays and by use of the BD Matrigel tumor invasion system. Cells were exposed to 0.0, 5.0, 10.0, or 20.0 μM GLA for 48 h. Epidermal growth factor (EGF) functioned as a chemoattractant for cancer migration and invasion. GLA reduced the migratory and invasive capacities of (a, top) MDA-MB-231 and (a, bottom) BT-549 cells. (b) Numbers of migrating/invading MDA-MB-231 cells treated with GLA. (c) Numbers of migrating/invading BT-549 cells treated with GLA (mean ± SD, n = 5).