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. 2014 May 21;105(7):875–882. doi: 10.1111/cas.12426

Figure 4.

Figure 4

Effects of glabridin (GLA) on epithelial–mesenchymal transition markers and miR-200s in MDA-MB-231 breast cancer xenografts. Nude mice bearing breast cancers were treated with the vehicle or with GLA (20 mg/kg/d). (a, top) RT-PCR analyses and (b) relative mRNA levels of E-cadherin and vimentin (mean ± SD, n = 3). (a, bottom) Western blot analyses and (c) relative protein levels of E-cadherin and vimentin (mean ± SD, n = 3). (d) Quantitative RT-PCR analysis of miR-200a, miR-200b, miR-200c, miR-141 and miR-429. Con, control. **P < 0.01 compared with medium control MDA-MB-231 cells.