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. 1977 Sep;74(9):3947–3950. doi: 10.1073/pnas.74.9.3947

Mutator action by Escherichia coli strains carrying dnaE mutations

C G Sevastopoulos 1,*, D A Glaser 1,†
PMCID: PMC431795  PMID: 333443

Abstract

Several newly isolated temperature-sensitive dnaE mutants of Escherichia coli exhibit powerful mutagenic action at permissive temperatures. Mutation rates for the two most active mutants were assayed at four different temperatures and compared to wild-type behavior. Temperature-resistant revertants of the original temperature-sensitive dnaE mutants exhibited lower, nearly normal, mutation rates, but no antimutator strains were found.

Keywords: spontaneous mutation, DNA replication

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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