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. 2014 Feb 12;105(3):252–257. doi: 10.1111/cas.12349

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© 2014 The Authors. Cancer Science published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Time-course analysis of the effect lycopene on cell-cycle progression and apoptosis determined by flow cytometry. Representative cell-cycle distributions after exposure to 50 μM lycopene for 0, 72 and 120 h. MCF-7 (a), SK-BR-3 (b) and MBA-MB-468 (c). Percentages of the total cell population in the different phases of cell cycle are also shown as column bars in the right panels of each cell line. Mean ± SD of three independent experiments. *Significant difference versus vehicle control. P < 0.05.