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. Author manuscript; available in PMC: 2015 Apr 4.
Published in final edited form as: Adv Chem Phys. 2014 Apr 4;155:1–68. doi: 10.1002/9781118755815.ch01

Fig. 11.

Fig. 11

(A) In vitro assembly of HIV CA protein into tubes monitored by absorbance (red diamonds, with thick grey lines indicating error bars) at indicated subunit concentrations compared to best fits using a rate equation model (black lines). (B) Light scattering for HPV LP1 assembly from Casini et al. [44] (light grey diamonds) compared to a continuous time Monte Carlo trajectory using parameters optimized to the data (solid black line). The dashed curve corresponds to a trajectory with parameter values reduced by 2.5 × 105 from their optimal values and negative values truncated to zero, to simulate a threshold level of signal to background scattering. (A) is reprinted with permission from Biochemistry, 51, 4416-4428 (2012), A Trimer of Dimers Is the Basic Building Block for Human Immunodeficiency Virus-1 Capsid Assembly, Tsiang, Niedziela-Majka, Hung, Jin, Hu, Yant, Samuel, Liu, Sakowicz, Copyright (2012) American Chemical Society. (B) is reprinted with permission from Phys. Biol., 7, 045005 (2010), Kumar and Schwartz, A parameter estimation technique for stochastic self-assembly systems and its application to human papillomavirus self-assembly, Copyright (2010) IOP Publishing.