Tab. 1.

Antimicrobial activities of potassium 8-R¹-9-R²-10-R³-3-R-2-oxo-2H-[1, 2, 4]triazino[2, 3-c]quinazoline-6-thiolates

Comp.	R	R1 = R2 = R3 = H (if not specified)	Investigated strains
			E. coli		S. aureus		P. aeruginosa		C. albicans
			MIC μg/mL	MBC μg/mL	MIC μg/mL	MBC μg/mL	MIC μg/mL	MBC μg/mL	MIC μg/mL	MBC μg/mL
2.1	CH3		100	100	50	200	50	200	100	100
2.2	C6H5		100	200	25	100	100	200	50	100
2.3	C6H4(CH3)-p		50	100	12.5	100	100	200	100	100
2.4	C6H4(CH3)2-3,4		100	100	100	200	50	100	50	100
2.5	C6H4(C2H5)-p		100	100	12.5	50	100	100	50	100
2.6	C6H4(i-C3H7)-p		100	100	25	50	50	100	50	100
2.7	C6H4(tert-C4H9)-p		50	100	6.25	12.5	50	100	100	100
2.8	C6H4(OCH3)-p		100	200	100	200	50	200	50	100
2.9	C6H4(OC2H5)-p		100	100	25	100	50	100	50	100
2.10	C6H4F-p		50	50	12.5	50	50	100	50	100
2.11	C6H5	R1 = CH3	100	100	25	100	50	200	50	100
2.12	C6H5	R2= F	100	200	6.25	25	100	200	50	50
2.13	C6H4F-p	R2= F	100	200	6.25	25	50	100	50	100
2.15	C6H5	R3 = Cl	100	200	6.25	100	50	100	50	50
2.16	C6H4(CH3)-p	R3 = Cl	100	200	6.25	100	100	100	50	100
2.17	C6H4(OCH3)-p	R3 = Cl	100	200	12.5	100	50	100	100	100
2.18	C6H4F-p	R3 = Cl	100	200	12.5	50	100	200	50	50
2.19	C6H4F-p	R1 = Br	100	200	12.5	25	50	100	50	100
2.20	C6H4F-p	R2 = Br	100	200	6.25	25	100	200	50	100
2.21	C6H5	R3 = Br	100	200	6.25	50	50	200	50	50
2.22	C6H4(CH3)-p	R3 = Br	100	200	12.5	50	50	100	50	50
2.23	C6H4F-p	R3 = Br	100	200	6.25	25	50	200	50	50
2.24	C6H4(OCH3)-p	R3 = Br	100	200	12.5	200	100	100	100	100
2.25	C6H4F-p	R3 = 1	100	200	6.25	200	100	200	50	50
2.26	C6H4(OCH3)-p	R3 = l	100	200	50	200	100	100	50	50
Trimethoprim		–	50	50	31.2	62.5	62.5	125	62.5	125
Nitrofural		–	1.5	–	6.25	–	6.25	–	25.0	–