Tab. 2.

Antimicrobial activities 8-R¹-9-R²-10-R³-3-R-6-thio-6,7-dihydro-2H-[1, 2, 4]triazino[2, 3-c]quinazoline-2-ones (3.1–3.26)

Comp.	R	R1 = R2 = R3 = H (if not specified)	Investigated strains
			E. coli		S. aureus		P. aeruginosa		C. albicans
			MIC μg/mL	MBC μg/mL	MIC μg/mL	MBC μg/mL	MIC μg/mL	MBC μg/mL	MIC μg/mL	MBC μg/mL
3.1	CH3		100	100	100	200	50	200	100	100
3.2	C6H5		50	100	12.5	50	100	100	100	100
3.3	C6H4(CH3)-p		50	50	12.5	100	50	100	50	50
3.4	C6H4(CH3)2-3,4		50	100	100	200	50	100	50	100
3.5	C6H4(C2H5)-p		50	50	12.5	25	50	100	100	100
3.6	C6H4(i-C3H7)-p		50	100	12.5	50	50	100	100	100
3.7	C6H4(tert-C4H9)-p		50	100	6.25	12.5	50	200	50	100
3.9	C6H4(OC2H5)-p		100	100	25	100	50	100	100	100
3.10	C6H4F-p		50	100	12.5	50	50	200	50	100
3.11	C6H5	R1 = CH3	50	100	25	50	100	100	50	100
2.11	C6H5	R3= F	100	200	6.25	50	100	200	50	50
2.15	C6H5	R3= F	100	200	6.25	50	100	200	50	50
3.16	C6H5(CH3)-p	R3 = Cl	100	200	12.5	100	100	200	50	100
3.18	C6H4F-p	R3 = Cl	100	200	25	25	50	100	100	100
3.19	C6H4F-p	R1 = Br	50	100	100	200	100	100	100	100
3.20	C6H4F-p	R2 = Br	100	200	25	50	50	200	50	50
3.21	C6H5	R3 = Br	100	200	25	25	100	200	50	50
3.22	C6H4(CH3)-p	R3 = Br	50	100	50	200	100	200	50	50
3.23	C6H4F-p	R3 = Br	100	200	12.5	50	50	200	50	50
3.24	C6H4(OCH3)-p	R3 = Br	100	200	12.5	200	100	200	50	50
Trimethoprim		–	50	50	31.2	62,5	62.5	125	62.5	125
Nitrofural		–	1,5	–	6.25	–	6.25	–	25.0	–