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. 2014 Sep 17;15(9):461. doi: 10.1186/s13059-014-0461-8

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© Eiring and Deininger; licensee BioMed Central Ltd. 2014

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Silent mutations increase with the total number of mutations per cell clone. The graph represents the total number of silent mutations per clone (x-axis) and the percentage of clones with at least one silent mutation (blue bars). White bars represent the expected percentage of mutations. Adapted with permission from Khorashad et al. [52].