Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
When HPV-related squamous cell carcinomas metastasize to lymph nodes, they often undergo cystic degeneration (A, hematoxylin and eosin stain). Documenting the presence of HPV by p16 immunohistochemistry (B) and/or HPV DNA in situ hybridization (B inset showing dot-like in situ hybridization signals in tumor nuclei) provides strong support for oropharyngeal origin.
