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a–c: sagittal slice (0.7 mm) of a mouse leg bearing a tumor. a. R2e image from ESE; b. R1e image from IRESE; and c. [trityl] image from ESE. The tumor contour is obtained from a registered MRI. d–f: stacked histograms of d. R2e; e. R1e; and f. the difference between R1e and R2e.