Table 4.
Determinants of colonization with PVL positive S. aureus.
| Characteristics | PVL positive S. aureus (n = 40) | PVL negative S. aureus (n = 85) | Crude OR (95%CI) | P | Adjusted ORc (95%CI) | Pc |
|---|---|---|---|---|---|---|
| Use of antimicrobials | 26 (65.0%) | 36 (42.4%) | 2.5 (1.1–6.0) | 0.02 | 2.0 (0.8–4.6) | 0.13 |
| Cotrimoxazole usea | 10 (25.0%) | 10 (11.8%) | 2.5 (0.8–7.4) | 0.06 | ||
| Abscessa | 11 (27.5%) | 13 (15.3%) | 2.1 (0.8–5.7) | 0.1 | ||
| Any SSTIa,b | 20 (50.0%) | 23 (27.1%) | 2.7 (1.1–6.3) | 0.01 | 2.6 (1.2–5.7) | 0.02 |
| Cotrimoxazole resistance | 37 (92.5%) | 28 (32.9%) | 25.1 (6.9–134.4) | <0.001 | 26.0 (7.2–93.8) | <0.001 |
| S. aureus ST15 | 21 (52.5%) | 14 (16.5%) | 5.6 (2.2–14.2) | <0.001 | 5.4 (2.3–12.7) | <0.001 |
| S. aureus ST152 | 17 (42.5%) | 1 (1.2%) | 62.1 (8.5–2584.6) | <0.001 | 65.6 (8.1–532.7) | <0.001 |
Data are n (%) of subjects. SSTI, skin and soft tissue infection. Eight carriers were colonized with two different isolates resulting in 125 isolates from 117 colonized individuals. ain the past 6 months. bany SSTI: wound infection, carbuncle/furuncle, abscess, pyodermatitis, cadjusted for HIV infection.