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. Author manuscript; available in PMC: 2015 Feb 5.
Published in final edited form as: Exp Neurol. 2008 Jun 9;213(2):268–280. doi: 10.1016/j.expneurol.2008.05.023

Figure 3.

Figure 3

Characteristics of PPN spike trains in the urethane-anesthetized preparation. Oscillatory activity in PPN spike trains (A, n=59 PPN cells in 17 intact rats, 38 cells in 11 lesioned rats) was determined by converting PPN spike trains to Gaussian waveforms with a 20 Hz sampling rate and then using FFT to determine power in the 0.3-2.5 Hz range. There is an increase in power in the ∼1 Hz range in PPN spike trains following dopamine cell lesion (left) with a significant increase in total power between 0.3-2.5 Hz following dopamine cell lesion (right). * P<0.05 compared with intact. Firing rate distributions (B, n=59 cells in 17 intact rats, 38 cells in 11 lesioned rats) are indicated for the intact and 6-OHDA lesioned animals. There was no significant difference in firing rate between intact and lesioned rats.