Fig 6. Red blood cell density changes in infected vervet monkeys treated with experimental drugs.

Monkeys were infected with T. b. rhodesiense KETRI 2537 and upon confirmation of onset of second stage HAT, treated with (A) DB829 or (B) DB868. DB829 was administered intramuscularly for either 5 consecutive days (28–32 days post-infection) or 5 alternate (*) days (28, 30, 32, 34 and 36 days post-infection). DB868 was administered orally for 10 consecutive days (28–37 days post-infection). Symbols represent means (A; n = 2) or means and standard error of the mean (B; n = 4).