Table 3. Time to clearance of trypanosomes from body fluids of monkeys treated with DB829 or DB868.

Monkey ID	Drug (Route)	Dose regimen	Time to initial clearance of trypanosomes from body fluids (blood and CSF) (days post-LDD)	Time to relapse (days post-LDD)
569F	DB829 (IM)	5mg/kg × 5 days, consecutive-day dosing 28–32 DPI	1	N/A
659M			1	N/A
668M	DB829 (IM)	5 mg/kg × 5 days, alternate-day dosing (28, 30, 30, 32, 34 and 36 DPI)	1	N/A
676F			1	N/A
546M	DB829 (IM)	5mg/kg × 5 days, consecutive-day dosing 28–32 DPI	4	N/A
693F			7	N/A
573F	DB868 (Oral)	20 mg/kg × 10 days, 28–37 DPI	7	77
679F			1	N/A
689M			1	161
696M			4	133
688M	DB868 (Oral)	10 mg/kg × 10 days, 28–37 DPI	1	56
690F			1	N/A
695M			1	28
697F			1	28
670F	DB868 (Oral)	3 mg/kg × 10 days, 28–37 DPI	N/A	N/A
687M			7	14

Key: F, female; M, male; IM, intramuscular; DPI, days post-infection; CSF, cerebrospinal fluid; LDD, last drug dose;

N/A, not applicable (monkey did not relapse)