Table 3.

IgG4-negative IgG4-related kidney disease

Pt no.	Age/sex	Allergy	Histological findings	IgG4 IHC (cells/HPF)	Renal CT findings	IgG/IgG4 (mg/dl)	C3/C4 (mg/dl)	sCr (mg/dl)	Eo (/μl)	IgE(IU/ml)	Extrarenal lesions	Steroid response	References
1	56/M	none	pTIN, MGN	IgG4/IgG <2%	mLDL	4193/7.5	25/1	2.75	782	547	Sa, AIP, LN	Good	Makiishi et al. [66▪]
2	74/M	AR, BA, EP	pTIN	infrequent (<10)	mLDL	5593/20	40/1	0.71	1475	352	Sa, AIP, Lu, P, LN	Good	Hara et al. [67▪]

AIP, autoimmune pancreatitis; AR, allergic rhinitis; BA, bronchial asthma; Eo, eosinophil; EP, eosinophilic pneumonia; HPF, high power field; IHC, immunohistochemistry; LN, lymphadenitis; Lu, lung lesion; MGN, membranous glomerulonephritis; mLDL, multiple low-density lesions; P, prostatitis; pTIN, plasma cell rich tubulointerstitial nephritis; Sa, sialadenitis; sCr, serum creatinine.