Table 3. Carotid and hemodynamic parameters with saline (control) and ascorbic acid infusions.
| Variable | Premenopausal (n = 24) | Early perimenopausal (n = 21) | Late perimenopausal (n = 21) | Postmenopausal (n = 31) |
|---|---|---|---|---|
| Carotid diameter, mm | ||||
| Saline | 6.12 (0.46) | 6.06 (0.59) | 5.93 (0.38) | 6.14 (0.41) |
| Ascorbic acid | 6.21 (0.46) | 6.32 (0.60)a | 6.05 (0.41) | 6.28 (0.42) |
| Brachial systolic blood pressure, mm Hg | ||||
| Saline | 105 (11) | 108 (9) | 113 (16) | 122 (15)b,c |
| Ascorbic acid | 105 (11) | 109 (11) | 113 (15) | 120 (17) |
| Brachial pulse pressure, mm Hg | ||||
| Saline | 39 (7) | 39 (6) | 44 (10) | 51 (12)b,c |
| Ascorbic acid | 39 (8) | 41 (5) | 44 (10) | 50 (11) |
Data are presented as mean (SD).
a
P < 0.05 versus saline.
b
P < 0.001 versus premenopausal.
c
P < 0.05 versus early perimenopausal.