Table 2.

Association between SCOPI-OCD score and PARKIN status among PD probands and asymptomatic first degree relatives in linear models

	PD probands			Asymptomatic relatives
SCOPI-OCD score		Mean difference in SCOPI OCD score compared to non-carriers (95% CI) p-value			Mean difference in SCOPI OCD score compared to non-carriers (95% CI) p-value
	Non-carriers	PARKIN 1 mutation	PARKIN 2 mutations	Non-carriers	PARKIN 1 mutation	PARKIN 2 mutations
Unadjusted model	45.1	−10.2 −21.3 to +0.9 p=0.07	−13.2 −23.9 to −2.6 p=0.02	36.9	+7.3 +0.005 to +14.6 p=0.05	+22.5 +3.7 to +41.72 p=0.02
Model 1: adjusted for age, gender, language, disease duration, levodopa equivalent and ropinirole equivalent doses (in PD), and MCI (in asymptomatic)	48.7	−13.9 −26.1 to −1.6 p=0.03	−24.1 −38.5 to −9.7 p=0.001	36.9	+7.2 −0.005 to +14.3 0.05	+15.4 −4.4 to +35.3 0.13
Model 2: Model 1 + depression (based on BDI≥15)	47.9	−11.9 −24.1 to + 0.3 p=0.06	−21.6 −36.1 to – 7.1 p=0.004	36.6	+8.2 +1.5 to +15.0 p=0.02	+8.1 −2.5 to +18.7 p=0.14

Note. SCOPI-OCD = Schedule of Compulsions, Obsessions and Pathological Impulses – Obsessive-Compulsive subscales. BDI = Beck Depression Inventory.