Fig. 7.

Based on the cumulative concentration-response (C-R) curves of rocuronium on ST (A), PTT (B) and ETT (C), MgCl₂ shifts the C-R curves of rocuronium to the left; hence, it increases the potency of rocuronium. The concentration of rocuronium is transformed to log concentration. Data are presented as mean ± SEM. The unit of concentrations for Mg is mM. n is the number of experiments. Mg: magnesium chloride, Rc: rocuronium, ST: single twitch, PTT: peak tetanic tension, and ETT: end tetanic tension. ^*P < 0.05, vs. Mg 1 mM by t-test with Bonferroni's correction.