Table 4.
PTH by Phenotypes of Hyperaldosteronism
| Phenotypes | “Primary HA-Like” (ALDO >15 ng/dl, PRA <0.6 ng/ml · h) | “Normal” (ALDO <12 ng/dl, PRA 1–2 ng/ml · h) | “Secondary HA-Like” (ALDO >15 ng/dl, PRA >2 ng/ml · h) | P Value (Primary vs Normal) | P Value (Secondary vs Normal) | P Value (Primary Versus Secondary) |
|---|---|---|---|---|---|---|
| n | 298 | 66 | 124 | — | — | — |
| Aldosterone, ng/dl | 21.2 (6.7) | 8.3 (2.6) | 26.6 (12.0) | <.0001 | <.0001 | <.0001 |
| PRA, ng/ml · h | 0.3 (0.2) | 1.4 (0.2) | 7.5 (7.7) | <.0001 | <.0001 | <.0001 |
| ARR | 146.0 (283.9) | 6.3 (2.3) | 6.4 (4.4) | <.0001 | .85 | <.0001 |
| Serum calcium, mg/dl | 9.6 (0.4) | 9.7 (0.3) | 9.6 (0.4) | .39 | .71 | .30 |
| Serum phosphate, mg/dl | 3.7 (0.5) | 3.6 (0.5) | 3.6 (0.5) | .24 | .74 | .30 |
| PTH, pg/ml | 50.2 (21.1) | 40.3 (16.3) | 43.0 (18.1) | <.0001 | .32 | <.001 |
Abbreviation: ALDO, aldosterone; ARR, aldosterone-to-renin ratio.
P values indicate statistical significance between indicated columns. Values represent means with standard deviation.