Table 3.
Effects of 12-Week Treatment With rhGH
| Baseline | 3 mo | Change | P | |
|---|---|---|---|---|
| Weight, kg | 116.3 ± 4.7 | 116.1 ± 4.9 | −0.2 ± 0.6 | .69 |
| BMI, kg/m2 | 37.8 ± 1.5 | 37.7 ± 1.6 | −0.1 ± 0.2 | .52 |
| Waist circumference, cm | 124 ± 3 | 121 ± 3 | −3 ± 1 | .03 |
| Total fat mass, kg | 44.4 ± 3.1 | 43.9 ± 3.1 | −0.5 ± 0.7 | .47 |
| Total LBM, kg | 70.3 ± 1.8 | 70.7 ± 2 | 0.4 ± 0.7 | .56 |
| Right lower extremity lean mass, kg | 12.0 ± 0.4 | 12.0 ± 0.4 | −0.05 ± 0.1 | .73 |
| Fasting glucose, mg/dL | 88 ± 2 | 94 ± 4 | 6 ± 3 | .04 |
| 2-h Glucose, mg/dL | 120 ± 9 | 134 ± 12 | 14 ± 10 | .16 |
| Fasting insulin, μIU/mL | 8.9 ± 1.3 | 15.8 ± 2.8 | 6.9 ± 2.7 | .02 |
| HOMA | 2 ± 0.3 | 3.9 ± 0.8 | 1.9 ± 0.8 | .03 |
| hsCRP, mg/L | 3.53 ± 0.44 | 1.74 ± 0.40 | −1.78 ± 0.57 | .008 |
| REE, kcal/d | 1757 ± 65 | 1922 ± 55 | 166 ± 51 | .006 |
| REE/LBM, kcal/d/kg | 24.98 ± 0.71 | 27.28 ± 0.68 | 2.30 ± 0.77 | .01 |
| Respiratory quotient | 0.88 ± 0.01 | 0.86 ± 0.02 | −0.02 ± 0.02 | .29 |
| VO2, L/min | 0.25 ± 0.009 | 0.27 ± 0.008 | 0.03 ± 0.008 | .005 |
| VCO2, L/min | 0.22 ± 0.009 | 0.24 ± 0.009 | 0.02 ± 0.008 | .05 |
Statistical analyses were performed with paired Student's t test.