Table 1.
Patient and primary tumor characteristics
| Characteristics | N |
| Median age (range, minimum–maximum) | 44 (27–79) |
| Stage of breast cancera | |
| I and II | 21 (51%) |
| III and IV | 20 (49%) |
| Histologic grade (n = 37) | |
| Well differentiated | 2 (5%) |
| Intermediately differentiated | 13 (35%) |
| Poorly differentiated | 22 (60%) |
| Tumor histology (n = 37) | |
| Invasive ductal carcinoma | 30 (81%) |
| Invasive lobular carcinoma | 2 (5%) |
| Invasive ductal and lobular mixed type | 4 (11%) |
| Invasive cancer | 1 (3%) |
| CCR7 (n = 29) | |
| + | 3 (10%) |
| − | 26 (90%) |
| CXCR4 (n = 29) | |
| + | 16 (55%) |
| − | 13 (45%) |
| HER2-neu (n = 39) | |
| + | 11 (27 %) |
| − | 28 (73 %) |
| CXCR4/HER2-neu (n = 29) | |
| + | 5 (17%) |
| − | 24 (83%) |
| ER (n = 36) | |
| + | 24 (67%) |
| − | 12 (33%) |
| PR (n = 33) | |
| + | 18 (55%) |
| − | 15 (45%) |
a
Sixth edition of American Joint Committee on Cancer Staging Manual.
bMissing cases were excluded from the analyses.
ER, estrogen receptor; PR, progesterone receptor.