Table 1. Characteristics of Older Five-Year Survivors of Early Breast Cancer and Matched Comparison Cohort.
| Breast Cancer Survivor Cohort* (n = 1,361) |
Comparison Cohort† (n = 1,361) |
||||
|---|---|---|---|---|---|
| No. | % | No. | % | ||
| Sociodemographic | |||||
| Age Category at Beginning of Follow-up (years) | |||||
| 70-74 | 502 | 37 | 502 | 37 | |
| 75-79 | 417 | 31 | 417 | 31 | |
| 80+ | 442 | 32 | 442 | 32 | |
| Race/ethnicity | |||||
| Caucasian, Non-Hispanic | 1115 | 82 | 1147 | 84 | |
| African-American, Non-Hispanic | 137 | 10 | 125 | 9.2 | |
| Hispanic | 72 | 5.3 | 62 | 4.6 | |
| Asian/Pacific Islander | 37 | 2.7 | 27 | 2.0 | |
| Native American | 0 | 0 | 0 | 0 | |
| Comorbidity Burden at Five Years after Index Date | |||||
| Prevalent Comorbidities included in mCCI ‡ (index weight) | |||||
| Myocardial infarction | (1) | 80 | 5.9 | 80 | 5.9 |
| Congestive heart failure | (1) | 140 | 10 | 117 | 8.6 |
| Peripheral vascular disease | (1) | 60 | 4.4 | 67 | 4.9 |
| Cerebrovascular disease | (1) | 96 | 7.1 | 98 | 7.2 |
| Dementia | (1) | 64 | 4.7 | 76 | 5.6 |
| Chronic pulmonary disease | (1) | 172 | 13 | 184 | 14 |
| Connective tissue disease | (1) | 36 | 2.6 | 62 | 4.6 |
| Ulcer disease | (1) | 75 | 5.5 | 73 | 5.4 |
| Diabetes | (1) | 202 | 15 | 169 | 12 |
| Mild liver disease | (1) | 7 | 0.51 | 6 | 0.44 |
| Hemiplegia | (2) | 24 | 1.8 | 25 | 1.8 |
| Moderate or severe renal disease | (2) | 17 | 1.2 | 15 | 1.1 |
| Diabetes with end organ damage | (2) | 31 | 2.3 | 31 | 2.3 |
| Leukemia, lymphoma or tumor d | (2) | 112 | 8.2 | 75 | 5.5 |
| Moderate or severe liver disease | (3) | 14 | 1.0 | 2 | 0.15 |
| AIDS | (6) | 0 | 0.00 | 0 | 0.00 |
| Metastatic solid tumor | (6) | 6 | 0.44 | 4 | 0.29 |
| Modified Charlson Comorbidity Index §,¶ | |||||
| mCCI 0 | 741 | 54 | 755 | 55 | |
| mCCI 1-2 | 502 | 37 | 487 | 36 | |
| mCCI 3+ | 118 | 8.7 | 119 | 8.7 | |
Older five-year breast cancer survivors diagnosed 1990–1994 with early stage I and II breast cancer at age 65 or older followed for 10 years beginning on the first day of the sixth year after index date (date of breast cancer diagnosis).
Comparison cohort matched for health system and age, who were free of breast cancer at matched enrollment date and followed for 10 years beginning on the first day of the sixth year after index date (date of matched breast cancer patient's diagnosis).
Participants may be counted in multiple comorbidities.
Prevalent breast cancer at enrollment date excluded.
Prevalent breast cancer at enrollment date excluded from modified Charlson Comorbidity Index (mCCI), which is calculated from the sum of comorbidity weights listed in the table (Charlson et al 1987).