Figure 1. Anatomical locations of thermogenic adipocytes in mice and humans.

(A) In rodents, interscapular BAT and perirenal BAT are composed of classical brown adipocytes. Beige adipocytes are largely found in subcutaneous WAT (anterior and inguinal WAT) and are highly recruitable (a process referred to as “browning” of WAT) by certain external cues. (B) Adult human BAT is located mainly in the cervical, supraclavicular, and paravertebral regions. In infants, BAT is found in the interscapular and perirenal regions.