Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Feb 6;6:63. doi: 10.3389/fmicb.2015.00063

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 Riva, Korhonen and Meri.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

C3 inactivation by S. enterica in serum. (A) S. enterica 14028R and 14028R-1 or (B) 14028R-1 strains complemented with PgtE (pMRK3), PgtE D206A (pMRK31) or empty vector (pSE380), were incubated in 5% NHS-VBS or in plain VBS for 1 h and pelleted. The reduced supernatants and washed pellets were immunoblotted with anti-C3c and -C3d antibodies. The cleavage fragments of C3 and the non-specific signal from bacteria-originating epitopes are indicated. PgtE-mediated cleavages are marked with asterices (^*).