Figure 8. A transcription factor code can uniquely identify the developmental age and anatomic structure in a sample profiled by microarray.
(A) 14 genes can distinguish six brain structures at 4 ages; in this example, three atlas structures at E18.5 (gray shade) remain indistinguishable with this code. (B) Identifying the anatomic region and biological age of a microarray sample based upon the TF code. For each sample, the GEO ID is given; the best match to a given age x region combination in the ADMBA is color-coded (red, high correlation; blue, low correlation; asterisk, best match). In each case, the TF code accurately identifies the closest age x brain structure. Note the anatomic criteria used for obtaining the microarray samples may have differed in part with our criteria, leading to the dispersion of the correlative results (see also Figures S7 and S8).