Chemical structure of axitinib. Axitinib has the chemical name N-methyl-2-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]-benzamide. The molecular formula is C22H18N4OS, and the molecular weight is 386.47 Da. Axitinib is a white to light yellow powder, weak base, nonhygrospic, classified as low solubility, high permeability [3].