Table 1. Effect of hypothyroidism and T2 administration to hypothyroid rats on rat resting energy expenditure and on the contribution of different tissues to rat total body weight.
Eu | Hypo | H+T2 1w | |
---|---|---|---|
Total T3 serum level (nM) | 0.88 ± 0.06 | 0.20 ± 0.04* | 0.23 ± 0.04* |
Total T4 serum level (nM) | 55.6 ± 3.0 | 7.1 ± 0.9* | 7.3 ± 0.9* |
Energy expenditure at rest Kcal produced/day·Kg0.75 | 73.2± 4.2 | 52.0 ± 3.5 * | 61.2±2.2*,# |
Food intake (gr) | 444±19 | 317±7* | 345±15* |
I-BAT/b.w. ×100 | 0.150 ± 0.008 | 0.131 ± 0.004* | 0.171±0.009# |
WAT(visceral depots)/b.w. × 100 | 4.6 ± 0.3 | 4.0 ± 0.2* | 3.6 ± 0.3* |
Liver /b.w. × 100 | 2.97 ± 0.12 | 2.72 ±0.01 | 2.79 ± 0.01 |
Gastrocnemius/b.w. × 100 | 1.12 ± 0.06 | 1.15 ±0.03 | 1.10 ± 0.05 |
Heart weight/b.w. × 100 | 0.27 ± 0.02 | 0.30 ±0.01 | 0.29 ± 0.01 |
Value are mean ± ES of 6 different rats.
*P<0,05 vs Euthyroid
#P<0,05 vs Hypothyroid rats.