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. 2015 Feb 6;10(2):e0116947. doi: 10.1371/journal.pone.0116947

Table 2. Body weight, gut organ growth and stomach pH of 17 d-old rats after gavage feeding with microbial-derived enzymes, i.e., a protease, amylase, lipase, and a mixture thereof, or water (control) during 14–16 days of age.

Body Stomach Stomach SI Proximal SI Distal SI Cecum Liver
weight weight pH length weight weight weight weight
Treatment g mg/g b.wt cm/g b.wt mg/g b.wt mg/g b.wt mg/g b.wt mg/g b.wt
Control 33.4 ± 1.1 6.8 ± 0.6 4.3 ± 0.2 1.4 ± 0.1 17.0 ± 2.3 14.5 ± 0.6 2.6 ± 0.5 33.5 ± 3.7
Protease 32.2 ± 1.2 7.2 ± 0.7 3.5 ± 0.3* 1.7 ± 0.1*** 24.7 ± 3.5*** 17.8 ± 2.5** 4.0 ± 0.5*** 35.8 ± 2.5
Amylase 35.5 ± 1.8 6.8 ± 0.4 4.0 ± 0.2 1.5 ± 0.0 16.6 ± 2.0 15.2 ± 2.3 2.5 ± 0.3 33.7 ± 1.3
Lipase 34.3 ± 1.6 7.0 ± 0.8 4.0 ± 0.3 1.5 ± 0.1 17.5 ± 1.7 15.2 ± 1.0 2.4 ± 0.4 34.5 ± 1.8
Mixture 32.5 ± 1.4 7.3 ± 0.5 3.4 ± 0.4* 1.7 ± 0.1*** 26.1 ± 2.3*** 17.6 ± 0.6*** 4.5 ± 0.4*** 37.37 ± 2.8*

The results (mean ± SD, n = 7) are presented per grams body weight (g b.wt). Significant differences between enzyme-treated and control groups are indicated by

* P < 0.05,

** P < 0.01,

*** P < 0.001; SI = small intestine.